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Nature

Graphene oxide-polydopamine membranes with controlled interlayer spacing

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10765-4 Polydopamine-pillared composite graphene oxide membranes with tunable and stable interlayer spacing, featuring controllable interlayer spacing, are capable of sieving hydrated rubidium and potassium ions and delivering continuous freshwater production at high levels.

Nature

Catalyst-free, microdroplet-mediated waste plastic conversion to diacids

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10746-7 A catalyst-free upcycling strategy based on in situ generation of hydroxyl radicals at microdroplet interfaces is described for efficient and scalable processing of polymers with minimal infrastructure, using only water and oxygen under mild conditions.

Nature

GPC3-specific dnTGFβRII-armoured CAR T cells for hepatocellular carcinoma

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10786-z Chimeric antigen receptor (CAR) T cells for antitumour therapy ‘armoured’ with a dominant-negative TGFβ receptor II show enhanced efficacy and tolerable safety in patients with advanced hepatocellular carcinoma who have developed resistance or not responded to previous treatment.

Nature

Magnetic character of the low-energy enhancement in <sup>70</sup>Zn

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10758-3 The low-energy enhancement in the γ-ray strength function of 70Zn is due to magnetic dipole transitions between nuclear states.

Nature

An encyclopedia of human enhancer–gene regulatory interactions

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10781-4 An encyclopedia of more than 92 million enhancer–gene regulatory interactions created as part of the ENCODE4 project provides a valuable resource for future studies of gene regulation and human genetics.

Nature

Fractional high-Chern insulator in twisted rhombohedral graphene

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10762-7 A rich variety of both integer and fractional high-Chern insulators are observed in a moiré system composed of Bernal bilayer graphene and rhombohedral tetralayer graphene.

Nature

Ketogenic diet mediates intestinal tumorigenesis through lipids not ketones

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10779-y A combination of different manipulations in mouse models of spontaneous intestinal adenoma formation dissects the roles of systemic and epithelial ketogenesis versus dietary lipids in ketogenic diet-mediated intestinal tumorigenesis, highlighting the need for nuanced consideration of dietary strategies for cancer prevention.

Nature

Cell-type signatures of Alzheimer’s disease shared across population groups

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10793-0 Single-nucleus RNA-seq and ATAC-seq analyses on post-mortem brain samples from African American, Latin and white individuals identify cell-type-specific molecular signatures that are associated with cognitive impairment and/or Alzheimer’s disease across diverse population groups.

Nature

People use fast and flat simulation to reason about new games

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10722-1 Large-scale behavioural studies show that people approach a new game systematically and adaptively rationally. A cognitive model called the ‘Intuitive Gamer’ offers insights into this process and may inform the design of more flexible AI systems.

Nature

Rarely categorical, highly separable representations along the cortical hierarchy

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10668-4 Cortical circuits prioritize diversity over categorical structure, supporting a computational regime geared towards high-dimensional, highly separable neural representations.

Nature

Rising dust pollution across Europe in a changing climate

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10743-w A database of daily dust metals in Europe is established and a machine learning model shows that transported dust intrusion events over the past decade are linked to changes in atmospheric circulation, while an ice core shows that the increase in dust since pre-industrial times is governed by increasing aridity in North Africa..

Nature

Metabolite glues as a means of purine sensing and chemotherapeutic response

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10790-3 Purines can act as endogenous molecular glues in human cells by anchoring a rate-limiting enzyme in purine biosynthesis to its inhibitor, and modifying this mechanism could provide a way to improve the properties of thiopurine chemotherapeutic drugs.

Nature

Regression to the mean can explain saturation of geomagnetic storms

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10757-4 The saturation of geomagnetic activity with solar wind strength can be explained by a regression to the mean effect, suggesting that the impact of extreme geomagnetic storms can be twice as large as previously thought

Nature

Programming fracture resistance in metamaterials via elastic instabilities

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10804-0 Elastic instabilities in mechanical metamaterials can be harnessed to programme fracture behaviour, transforming instability from a failure mechanism into a design principle that increases fracture energy by up to tenfold.

Nature

A Bayesian framework for longitudinal EHR and genetic discovery

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10780-5 A Bayesian generative framework that integrates longitudinal electronic health records with genetic data to identify latent disease signatures is presented.

Nature

Scalable quasi-pure MOF membranes for energy-efficient gas separations

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10655-9 Scalable quasi-pure metal–organic framework membranes achieve near-intrinsic separation performance, enabling energy-efficient industrial gas separations with major cost reductions compared with distillation.

Nature

Ammonia pressure controls colloidal metal nitride synthesis in molten salts

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10801-3 A molten salt, high-pressure synthesis method enables solution-based production of diverse refractory metal nitride nanocrystals, expanding access to technologically important nitride materials for advanced applications.

Nature

Quantum statistical plasmonic metacrystals

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10782-3 A new class of materials, quantum statistical plasmonic metacrystals, is described, which can selectively transmit different types of light based only on their quantum coherence, showing bands of allowed and forbidden photon statistics.

Nature

Food systems transformation would reshape global agriculture

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10775-2 Scenario simulations using global economic models show that by 2050 the transformation of food systems towards healthy diets, improved productivity and halving of food waste result in a restructuring of global agriculture.

Nature

Universal gates from braiding and fusing anyons on quantum hardware

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10709-y A 54-qubit realization of non-Abelian S3 topological order demonstrates that combining anyon braiding with fusion enables universal topological quantum computation.

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