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Parts of the U.S. are experiencing smoke from Canadian wildfires drifting down and rising summer temperatures, creating a potentially deadly situation, according to the American Heart Association, a relentless force changing the future of health for everyone everywhere.
Body Mass Index (BMI) has long been used in public health and clinical settings as a simple tool to classify an individual's physical status based on their height and weight. Originally developed in the 1830s by Belgian mathematician Adolphe Quetelet, BMI was designed to describe the characteristics of the average man rather than to assess an individual's health, and it did not account for age, sex, ethnicity or body composition.
Researchers at The University of Texas MD Anderson Cancer Center identified an immune pathway that may promote the progression of oral precancerous lesions into head and neck squamous cell carcinoma. These results provide insight into how precancers gradually establish immune tolerance that allows cancer development.
Recognizing that nurses are an untapped resource for health care solutions, Penn Nursing has released a comprehensive guide for institutions to build their own nurse-led innovation accelerators. The model, supported by the Bedford Falls Foundation, provides a structured pathway to move nurse-led ideas from simple "one-offs" to scalable, commercialized solutions.
A new study published in the Journal of the American College of Radiology (JACR) suggests that venture capital (VC) is playing a significant and growing role in driving innovation in radiology. The study, "Venture Capital Investments in Radiology from 2000–2023," found that a total of $11.4 billion was invested across 646 companies, with funding especially concentrated in medical devices, artificial intelligence health care software, and biotechnology and drug discovery.
A research team at Fujita Health University led by Professor Tsuyoshi Miyakawa has uncovered a novel mechanism of cellular plasticity in which repeated neuronal stimulation can durably alter the identity of mature neurons. Using a neural stimulation pattern termed "Repetitive Optogenetic Stimulation (REPOPS)," the researchers found that granule cells of the hippocampal dentate gyrus undergo long-lasting changes in nuclear structure and gene expression, revealing a novel process which the team terms "nuclear reprogramming."
For millions of stroke survivors, something as simple as picking up a glass of water or holding a sandwich is a daily challenge. Quentin Sanders wants to make those moments easier through wearable robotic technology designed to restore hand function.
As the Trump administration's January deadline looms for states to enforce new Medicaid work requirements, some state lawmakers are turning the tables by pushing to publicly name the largest companies that have employees enrolled in the government program covering low-income and disabled people.
Two papers by researchers and policy practitioners provide evidence-based suggestions to help Japan's health system continue to flourish, even as its population rapidly ages.
Breastfeeding is widely recognized for its important role in supporting a child's early growth and immune system development. Previous studies have found that exclusive breastfeeding for 4 to 6 months is associated with a lower risk of bronchial asthma and allergic rhinitis during early childhood. Recognizing these health benefits, the World Health Organization recommends exclusive breastfeeding for the first 6 months of life. Despite its positive effects, its impact on food allergies remains inconclusive.
For veterans with type 2 diabetes (T2D) receiving basal insulin therapy, the addition of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) does not increase the rate of insulin discontinuation compared with other glucose-lowering agents, according to a study published online July 14 in the Annals of Internal Medicine.
Migraines, digestive problems, anxiety and depression can be part of endometriosis, although they are often interpreted as separate conditions. Research led by the Sant Pau Research Institute (IR Sant Pau) and published in Human Reproduction has identified different symptom patterns in more than 22,000 women, reinforcing the idea that the disease extends far beyond its traditional gynecological manifestations.
Researchers at Umeå University have identified changes in the body's major antioxidant systems in patients with hereditary transthyretin (TTR) amyloidosis. The findings support the hypothesis that oxidative stress contributes to disease development and also identify new biomarkers that may help detect individuals at increased risk of developing the disease. The results have been published in the journal Biomarker Research.
Being overweight and obesity may contribute to significantly more cancer cases than previously thought. This is the conclusion reached by researchers at the German Cancer Research Center (DKFZ). Their analysis shows that when more accurate measures of body fat and methodological biases are considered, more than 10% of all cancer cases can be attributed to increased body weight—nearly twice as many as previous estimates suggested.
University of Manchester scientists have uncovered evidence that a buildup of a common body waste product in the brain could help drive two of the most devastating neurological diseases.
A study using positron emission tomography (PET) imaging has found that patients with schizophrenia had significantly lower muscarinic acetylcholine M1 receptor availability (about 13%–19%) across multiple brain regions than healthy individuals. Reduced M1 receptor availability affects several brain regions involved in cognition, learning, memory and executive function. The findings in Biological Psychiatry provide the first in vivo evidence supporting widespread M1 receptor deficits in schizophrenia.
The sharp fall in EU nurses joining the NHS after the Brexit referendum may have contributed to more than 1,200 additional patient deaths each year in England, according to new research led by the University of Surrey in partnership with the University of Aberdeen, Harvard Business School and Vienna University of Economics and Business (WU).
Cancer develops when the body's systems for controlling cell growth break down, allowing cells to multiply unchecked. Texas A&M researchers have identified two naturally occurring molecules that appear to help restore those controls, offering a potential new strategy for slowing the progression of lung cancer.
Perimenopause uncertainty is prevalent among 34% of women aged 35 years or older, according to a study published online July 14 in Menopause.
By analyzing individual cancer cells, researchers from the Université Libre de Bruxelles (ULB) discovered the transcriptional regulators governing epithelial-to-mesenchymal transition (EMT) in tumors and identified key master regulators that control metastasis, revealing potential therapeutic vulnerabilities to block metastatic dissemination.