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Ketogenic diet mediates intestinal tumorigenesis through lipids not ketones
Nature
Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10779-y
A combination of different manipulations in mouse models of spontaneous intestinal adenoma formation dissects the roles of systemic and epithelial ketogenesis versus dietary lipids in ketogenic diet-mediated intestinal tumorigenesis, highlighting the need for nuanced consideration of dietary strategies for cancer prevention. ...
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