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A new study led by researchers at Washington University School of Medicine in St. Louis has found that an investigational mRNA influenza vaccine helps the immune system recognize a wider range of influenza viruses than today's standard flu shot, offering stronger and potentially longer-lasting protection.
Researchers around the world are racing to develop new quantum-based systems for sensing, communication, computing and control that have the promise of outperforming traditional systems. Creating stable, measurable, distinguishable quantum states—which would be the heart of any such system—is a daunting task.
A new study published in Nature Communications has uncovered a communication pathway between mitochondria and RNA granules that may help scientists understand how the toxic buildup of the TDP-43 protein leads to the development of certain neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
The aftermath of a supernova, a stellar explosion, is usually a slowly fading cloud of hot gas. So when astronomers pointed NASA's Chandra X-ray Observatory at the nearby galaxy Messier 83 (M83), they did not expect to find a population of supernova remnants, or the debris from these explosions, showing dramatic changes in their brightness. The new results have been presented at the American Astronomical Society meeting in Pasadena, California, and published in The Astrophysical Journal.
Early results from a UCL- and UCLH-led clinical trial suggest that a type of CAR T-cell therapy—developed by Autolus Therapeutics, a UCL spinout—could offer a new treatment approach for people with severe, treatment-resistant lupus. The findings, presented at the EULAR European Congress of Rheumatology (EULAR 2026), come from the ongoing Phase I CARLYSLE study, which is evaluating obecabtagene autoleucel (obe-cel) in patients with severe refractory systemic lupus erythematosus (SLE). The early data indicate that the therapy has a favorable safety profile and may lead to meaningful improvements in disease activity.
Among patients with preexisting hypertension taking antihypertensive medications, glucagon-like peptide-1 receptor agonist (GLP-1 RA) use is associated with an increase in hypotensive-related events, according to a study presented at ENDO 2026, the annual meeting of the Endocrine Society, held from June 13 to 16 in Chicago.
Oxford's 2024 Word of the Year, "brain rot," refers to the loss of intelligence or critical thinking skills due to the overconsumption of specific types of content, most often in the digital sphere. A Binghamton University doctoral student has published findings that help explain how the structural forces of large tech companies make it difficult to focus, read and even engage in democracy.
Orthopedic implants are designed to restore movement and relieve pain, offering patients a second or even third chance at mobility. A hip or knee replacement is often framed as a durable fix, engineered to last for years, sometimes decades, inside the human body. And modern hip and knee implants exceed expectations, providing long service time and significantly improved quality of life for the vast majority of patients. But durability inside biology, especially the human body, is never static once a foreign material is introduced. It responds continuously, at every scale.
A clinical trial supported by the National Institutes of Health (NIH) found that adults with prediabetes assigned to a lifestyle intervention had a significantly lower risk of developing multiple chronic health conditions (known as multimorbidity) over time than those assigned to a placebo. This study, which followed participants for more than two decades, also found that participants assigned to receive metformin did not experience a statistically significant reduction in multimorbidity risk. The findings, published in JAMA, highlight the lasting benefits of lifestyle programs that may lower the risk of developing chronic conditions.
An international team of researchers report in the journal Nature Immunology that a mutation in the gene OTULIN causes pediatric-onset pyoderma gangrenosum, characterized by recurrent ulcerating skin sores. They classify the condition as a new inborn error of immunity (IEI)—one of a group of more than 500 genetic disorders that impair the development or function of the immune system.
The Ontong Java Plateau in the western Pacific Ocean is the largest oceanic plateau on Earth, and its formation mechanism has not been well understood.
New research is shedding light on how comparing ourselves to others affects happiness and life satisfaction. Led by McGill University researchers, the study shows that people who feel worse off financially than their peers are more likely to report signs of languishing, even when their actual income is similar. The paper is published in the journal Social Science & Medicine.
Researchers from the Terasaki Institute for Biomedical Innovation, together with key pioneers in glioma biology, neuro-oncology and stem cell biology, have published a comprehensive review in Society for Neuro-Oncology's journal Neuro-Oncology outlining the evolving landscape of glioma organoid technologies and proposing a foundational classification framework to guide translational brain tumor research.
Anti-T-lymphocyte globulin (ATLG) for the prevention of graft-versus-host disease (GvHD) reduces complications and infection-related mortality compared with post-transplant cyclophosphamide (PTCy) in allogeneic hematopoietic stem cell transplantation from unrelated donors. Although PTCy was associated with fewer cases of acute (Grade II–IV) and chronic GvHD, this did not result in a survival benefit for patients with blood cancer. These initial results from the GRAPPA study were presented by DKMS as a late-breaking abstract at the European Hematology Association Congress (EHA 2026) in Stockholm.
In January 2023, Debbie Martínez was selected as deputy director of the Research Services Directorate (RSD) at NASA’s Langley Research Center. She brings more than three decades of experience in aeronautics, project management, and cross‑agency collaboration. Previously, Martínez served as associate project manager for the IASP/Low Boom Flight Demonstrator (LBFD X‑59/Quesst) and AAVP/Commercial Supersonic Technology […] The post Debbie Martínez appeared first on NASA Science.
Researchers at the University of Maryland School of Medicine (UMSOM) have identified a target that may improve the response to CAR T-cell therapy, a treatment for patients with recurrent or difficult-to-treat blood cancers.
Human skeletal biologists traditionally provide sex estimations as part of establishing biological profiles (skeletal sex, age-at-death, stature, ancestry/population affinity) for skeletonized remains, often using the shapes and sizes of the pelvis, long bones and skull, among other bones in the body. While analytical methods portray skeletal sex differences as almost purely binary (female or male), a person's sex—including hormones, genetics, external anatomy, internal anatomy and the skeleton—can be more varied than either female or male.
A new study finds that adults who simply breathe in secondhand cigarette smoke have about 1.5 times more of the toxin cadmium in their blood than people in smoke-free environments.
A detailed cellular study of Crohn's disease has mapped how gene activity changes across more than 50 cell types in the gut. The study provides an open resource of the genes that characterize each cell type and those whose activity shifts in disease, uncovering new molecular and cellular signatures of immune activity in the gut lining.
Over 40,000 seamounts—undersea mountains that don't breach the ocean's surface—are scattered across the ocean floor. Some form linear chains, while others occur as dispersed, isolated features that are not part of well-defined volcanic chains.