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Understanding why some people stay healthy without developing disease until late in life (have an increased healthspan), whereas others become infirm at a much younger age, has important implications for the health of today's aging population. Life expectancy has significantly increased in the last two centuries, but healthspan has not kept pace.
About 25 million people in the U.S.—roughly eight out of 100—are diagnosed with asthma. Allergens, air pollution, extreme weather conditions and other irritants can cause chronic lung inflammation, leading to coughing, wheezing or shortness of breath.
Just 10 viral particles of the H5N1 bird flu that caused hundreds of influenza outbreaks in U.S. dairy cattle can cause infection in cows, a new study shows. The research also hints at why the outbreaks have confounded scientists, farmers and livestock handlers hoping to contain and prevent the disease—an effort likely complicated by the fact that the virus has an affinity for cow mammary glands rather than airways.
The "right to repair" movement is gaining steam as consumers push corporations to offer them more freedom to fix products—from cars to dishwashers to toys.
Patients with multiple myeloma who received a new immunotherapy combination lived significantly longer without their cancer worsening and showed early signs of improved survival in a large international clinical trial.
University of Mississippi researchers are studying how plants respond to heat at the molecular level, an important consideration for farmers, businesses and policymakers as global temperatures rise.
When a patient has made it to 85 years old in reasonable health, their instinct—and often their physician's—is to redouble prevention efforts, optimize every number and close every gap. I want to argue the opposite.
When stars like our sun age, they puff up into red giants. Their bubbling outer mass gradually escapes into space, and their remaining cores contract into white dwarfs. Since most stars end their lives this way, the universe is teeming with white dwarfs. A new study from Caltech's Jim Fuller, professor of theoretical astrophysics, proposes a new model of the final death throes of sun-like stars that shows how escaping mass from the stars' surfaces leads to a series of little kicks.
The world has never had more data, more models or more economists. It has rarely felt more out of control. Uncertainty, not risk, has become the defining condition of our era. Central bankers invoke it. Political leaders use it to defer decisions and justify extraordinary ones. Academics are struggling to adapt their theories to a brave new world of unexpected outcomes and erratic policy choices. The IMF's World Uncertainty Index—which tracks how often the word appears in economic and political reporting across 143 countries—has been running at historically elevated levels for the better part of a decade, with fresh spikes after every major shock.
A new study led by researchers at Washington University School of Medicine in St. Louis has found that an investigational mRNA influenza vaccine helps the immune system recognize a wider range of influenza viruses than today's standard flu shot, offering stronger and potentially longer-lasting protection.
Researchers around the world are racing to develop new quantum-based systems for sensing, communication, computing and control that have the promise of outperforming traditional systems. Creating stable, measurable, distinguishable quantum states—which would be the heart of any such system—is a daunting task.
A new study published in Nature Communications has uncovered a communication pathway between mitochondria and RNA granules that may help scientists understand how the toxic buildup of the TDP-43 protein leads to the development of certain neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
The aftermath of a supernova, a stellar explosion, is usually a slowly fading cloud of hot gas. So when astronomers pointed NASA's Chandra X-ray Observatory at the nearby galaxy Messier 83 (M83), they did not expect to find a population of supernova remnants, or the debris from these explosions, showing dramatic changes in their brightness. The new results have been presented at the American Astronomical Society meeting in Pasadena, California, and published in The Astrophysical Journal.
Early results from a UCL- and UCLH-led clinical trial suggest that a type of CAR T-cell therapy—developed by Autolus Therapeutics, a UCL spinout—could offer a new treatment approach for people with severe, treatment-resistant lupus. The findings, presented at the EULAR European Congress of Rheumatology (EULAR 2026), come from the ongoing Phase I CARLYSLE study, which is evaluating obecabtagene autoleucel (obe-cel) in patients with severe refractory systemic lupus erythematosus (SLE). The early data indicate that the therapy has a favorable safety profile and may lead to meaningful improvements in disease activity.
Among patients with preexisting hypertension taking antihypertensive medications, glucagon-like peptide-1 receptor agonist (GLP-1 RA) use is associated with an increase in hypotensive-related events, according to a study presented at ENDO 2026, the annual meeting of the Endocrine Society, held from June 13 to 16 in Chicago.
Oxford's 2024 Word of the Year, "brain rot," refers to the loss of intelligence or critical thinking skills due to the overconsumption of specific types of content, most often in the digital sphere. A Binghamton University doctoral student has published findings that help explain how the structural forces of large tech companies make it difficult to focus, read and even engage in democracy.
Orthopedic implants are designed to restore movement and relieve pain, offering patients a second or even third chance at mobility. A hip or knee replacement is often framed as a durable fix, engineered to last for years, sometimes decades, inside the human body. And modern hip and knee implants exceed expectations, providing long service time and significantly improved quality of life for the vast majority of patients. But durability inside biology, especially the human body, is never static once a foreign material is introduced. It responds continuously, at every scale.
A clinical trial supported by the National Institutes of Health (NIH) found that adults with prediabetes assigned to a lifestyle intervention had a significantly lower risk of developing multiple chronic health conditions (known as multimorbidity) over time than those assigned to a placebo. This study, which followed participants for more than two decades, also found that participants assigned to receive metformin did not experience a statistically significant reduction in multimorbidity risk. The findings, published in JAMA, highlight the lasting benefits of lifestyle programs that may lower the risk of developing chronic conditions.
An international team of researchers report in the journal Nature Immunology that a mutation in the gene OTULIN causes pediatric-onset pyoderma gangrenosum, characterized by recurrent ulcerating skin sores. They classify the condition as a new inborn error of immunity (IEI)—one of a group of more than 500 genetic disorders that impair the development or function of the immune system.
The Ontong Java Plateau in the western Pacific Ocean is the largest oceanic plateau on Earth, and its formation mechanism has not been well understood.