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Cancer cells are remarkably good at adapting to stress. When treatments damage them, they often find new ways to survive, fueling drug resistance and disease progression.
Most of my ecology and evolution undergraduates have never held a pair of binoculars or looked at a bug through a magnifying glass. They don't know how to use a key to identify a plant or insect, let alone why they should bother. They struggle to name common garden birds. They expect to learn about biodiversity from behind the safety of a computer screen. Fieldwork is considered a luxury or an inconvenience, depending on your tolerance for rain.
Researchers at the University of Cologne's Center for Molecular Medicine Cologne (CMMC) have discovered a previously unknown mechanism that makes most pancreatic cancer cells susceptible to a form of programmed cell death. The team, led by Professor Dr. Silvia von Karstedt, showed that cancer cells with mutations in the KRAS gene develop a vulnerability that can be used to eliminate tumor cells in preclinical models. The findings open up new perspectives for treating pancreatic cancer. The study "Oncogenic KRAS-Driven type I Interferon Signalling Primes Pancreatic Cancer for Necroptosis" was published in the journal Nature Communications.
For women's health providers, the Dobbs decision that rescinded abortion rights wasn't just an abstract political event.
A research team from Tohoku University and Kyocera Corp. has developed a new magneto-optical material—a nanocomposite magnetic garnet film—that can be deposited directly onto silicon substrates while delivering a magneto-optical figure of merit four times higher than conventional polycrystalline films.
Researchers at the University of Houston's College of Pharmacy have discovered an unexpectedly simple strategy to improve the performance of mRNA vaccines and gene therapeutics: adding salt. The findings, published in Small, address one of the biggest challenges facing modern gene medicine—getting fragile therapeutic material to the right place inside cells.
A new study by Prof. Gabriel Weimann, a senior researcher at the International Institute for Counter-Terrorism (ICT) at Reichman University and professor emeritus in the Department of Communication at the University of Haifa, and Daniel Haberfeld, a researcher and head of the Cyberterrorism Desk at ICT, explored the activities of the Handala hacker group, which is linked to Iran's Ministry of Intelligence and Security (MOIS). The study sought to determine whether the group's operations are best characterized as cyberterrorism or psychological warfare.
Snowfall deep inside East Antarctica has increased in recent decades, and distant ocean temperature changes may be partly responsible. Using long-term climate data and observations from Dome Fuji station, researchers found that the increase in snowfall is strongly linked to atmospheric blocking patterns that carry moist air into inland Antarctica. These patterns are, in turn, influenced by sea surface temperature changes in the subtropical South Atlantic Ocean—highlighting important climate connections across vast distances.
Some people might not mind spending time alone, but new research with data from 18 countries suggests that older people who struggle with loneliness—rather than strictly being alone—may experience faster mental and physical decline.
Nominate Yourself or a Colleague: NASA AI/ML STIG Leadership Council The post Nominate for NASA AI/ML STIG Leadership Council appeared first on NASA Science.
In contrast to classical digital media, short-video platforms are characterized by rapidly changing content, highly personalized recommendations and a targeted maximization of usage time. This is precisely where the study begins: It examines whether and how this specific design—and not just the content—can influence neurocognitive and emotional effects in adolescents and young adults.
In rocky planets such as Earth and Mars, the oxidation state of the mantle is thought to strongly influence the melting temperature of mantle materials (i.e., magma generation), the composition of volcanic gases, and ultimately the evolution of surface environments. In particular, during the solidification of the "magma ocean," which is believed to have been widespread during the early stages of planetary formation, the oxidation state in which iron is incorporated into minerals is considered crucial for understanding subsequent mantle evolution.
A new study demonstrates that honeybees can evaluate the reliability of their own communication, actively adjusting the vigor of their "waggle dance" based on the truthfulness of the information they provide. By manipulating whether a dancing bee's followers successfully found food, experiments revealed that only bees with verified, "honest" information increased their recruitment effort over time when advertising a new location, whereas "liar" or "unverified" bees did not. This internal self-control mechanism naturally filters out ambiguous or misleading signals, allowing the hive to function efficiently as a cooperative superorganism.
Artificial cells created in the laboratory offer a wide range of potential applications. Until now, however, their membranes—unlike those of real cells—have been virtually impermeable. Researchers at the Max Planck Institute for Polymer Research, led by Director Katharina Landfester, have now developed a new method to make the membranes of artificial cells more permeable to chemical substances. This prepares them for both medical research and future applications such as drug delivery. The scientists published their findings in the journal ACS Nano.
Federal health officials are mobilizing against the New World screwworm, a flesh-eating parasite recently detected in animals in the southwest United States.
Men are overrepresented when it comes to heart disease, but there are certain conditions that mainly affect women, such as "broken-heart syndrome." Stress and anxiety are common in this group. A new study led by researchers at Uppsala University and Karolinska Institutet shows that internet-based cognitive behavioral therapy (CBT) can reduce symptoms and help patients manage their emotions better.
The vast majority of Europe's beaches offer "excellent" water quality for swimming, the EU environment agency said Tuesday ahead of the summer season, with coastal nations and inland Austria topping the list.
New research by the University of Limerick in Ireland has found that collaborative sessions combining music therapy with speech and language therapy can support meaningful communication gains in young children recovering from acquired brain injuries.
An international research team led by Forschungszentrum Jülich and the IPK Leibniz Institute has developed an artificial intelligence model that predicts where regulatory proteins dock onto plant DNA to switch genes on and off. Trained entirely on the rich genomic data available for the model plant Arabidopsis thaliana, the model transfers successfully to crops such as maize—opening new ways to understand how genetic variation shapes crop performance. The study was recently published in Nature Communications.
Chronic stress, the prolonged exposure to psychological and/or physical strain, is known to be a risk factor for depression, anxiety and some other psychiatric disorders. Past studies suggest that chronic stress disrupts the integrity of myelin, a fatty insulating layer that surrounds nerve fibers and helps electrical signals travel efficiently between brain cells.