오픈뉴스백과
세계의 오늘한국의 오늘피드
뉴스
전체 뉴스진영별 의제회사정부과학학술용어사전뉴스로 배우기
커뮤니티제보
...

오픈뉴스백과

집단지성 기반 뉴스 검증 플랫폼. 다양한 시각으로 뉴스를 이해합니다.

서비스

세계의 오늘한국의 오늘뉴스정부과학학술용어사전소개

법적 고지

개인정보처리방침이용약관콘텐츠 이용 안내

문의

이메일 문의

본 플랫폼에서 제공하는 뉴스 콘텐츠의 저작권은 각 언론사에 있으며, 무단 복제 및 배포를 금지합니다.

RSS 피드를 통해 수집된 콘텐츠는 각 원저작자의 라이선스 조건을 따릅니다. 오픈 라이선스(CC-BY 등) 콘텐츠는 해당 라이선스에 따라 출처를 표기합니다.

오픈뉴스백과는 뉴스 집계 및 검증 플랫폼으로, 개별 기사의 내용에 대한 책임은 해당 언론사에 있습니다.

이용자가 작성한 피드백, 팩트체크, 독자 제보 등의 콘텐츠에 대한 책임은 해당 작성자에게 있습니다.

콘텐츠 제거 요청: contact@opennewspedia.com

© 2026 오픈뉴스백과 (OpenNewsPedia). All rights reserved.

📑

학술

arXiv 등 학술 논문. CC-BY 라이선스로 자유 재사용 가능 — 출처표시 시 상업 사용 OK.

총 453건

분야

전체arXiv CS.AI6,535arXiv Math6,523arXiv Physics2,314arXiv Stat1,122PLOS ONE453arXiv Q-Bio318arXiv Econ316PLOS Global Public Health64PLOS Biology29PLOS Medicine14
PLOS ONE

Analytical correlation between overall subjective satisfaction and criterion-based evaluation in continuing medical education: A cross-sectional study of associated factors

by Hela Ghali, Asma Ben Cheikh, Sana Bhiri, Latifa Lassoued, Imed Chouchen Background Continuing Medical Education (CME) is essential for updating the competencies of healthcare professionals. As part of a quality improvement initiative, the CPD committee at the Faculty of Medicine of Sousse evaluated the 2021–2022 programs. The study aimed to assess learner satisfaction by distinguishing overall subjective satisfaction from criterion-based evaluation (based on specific quality criteria like resources and pedagogy). This approach identifies whether a positive general feeling masks structural deficiencies in course design. Methods We conducted a cross-sectional study over a five-week period using a structured evaluation grid distributed via Google Forms. The evaluation covered all three phases of the CME process (before, during, and after the course). For each criterion, participants selected one of four options ranging from “unsatisfied” to “satisfied.” Criterion-based evaluation was assessed via an overall rating from 1 to 5, with a score ≥4 indicating satisfaction. Correlation between overall subjective satisfaction and criterion-based evaluation was analyzed. Results A total of 268 responses were collected. Women predominated (73.1%). The mean age was 36 ± 8 years, and most participants practiced in urban areas (91%) and at the tertiary care level (55.6%). The overall mean satisfaction score was 3.8 ± 1.02, with 69.4% of participants classified as satisfied. Overall subjective satisfaction was significantly associated with criterion-based evaluation across all criteria. In addition, overall subjective satisfaction was associated with age (p = 0.007), years in current practice (p = 0.043), academic affiliation (p = 0.008), specialty (p = 0.019), and type of CME (p = 0.003). Conclusion Learner satisfaction with CME activities was correlated with factors such as specialty, academic affiliation, experience, age, and CME format. These findings support recommendations to tailor CME content to participant profiles, emphasize practical training, ensure timely delivery of resources, and improve advance communication of schedules to enhance program effectiveness.

PLOS ONE

Local genetic correlations between systemic sclerosis and common cancer types

by Karina Patasova, Weng Ian Che, Helga Westerlind, Lina Marcela Diaz-Gallo, Marie Holmqvist Introduction The incidence of cancer, encompassing all major types, is significantly higher among patients with systemic sclerosis (SSc) compared to the general population. While previous studies have assessed the global genetic relationships between SSc and various cancers and found no evidence of causality or pleiotropy, these methods average effects across the genome and thus ignore potential opposing directional effects at different loci, thereby missing locus-specific associations. To address this gap, we assessed fine-scaled genetic overlap between SSc and commonly associated cancers, namely breast and lung cancers, as well as hematologic malignancies, by applying local genetic correlation analyses. Methods We assessed the genetic relationship between SSc and cancers that frequently co-occur with SSc: breast cancer and its’ four main molecular subtypes: HER2-enriched-like, luminal A and B-like, and triple-negative breast cancers, as well as lung cancer, lymphocytic leukemia, and non-Hodgkin's lymphoma. Published genome-wide association study statistics were obtained from the GWAS catalog and The Breast Cancer Association Consortium, and data were standardized, quality control filtered, and preprocessed. Global and local genetic correlations were evaluated using linkage disequilibrium score regression and Local Analysis of [co]Variant Annotation software. Gene-based cross-trait meta-analysis, colocalization and fine-mapping approaches were used to assess evidence of pleiotropy across regions identified by local genetic correlation analyses. We implemented visualization of the local genetic correlations and functional enrichment analyses of pleiotropic genes from these local correlations. Results We did not detect any significant global genetic correlation between SSc and the analyzed cancer subtypes. However, we identified 23 significant local bivariate correlations; 21 were with different molecular subtypes of breast cancer. However, only the locus shared between SSc and lung cancer showed strong evidence of pleiotropy. Genes within loci shared with lung cancer were involved in cell communication and signaling, extracellular matrix remodelling and skin morphogenesis. Conclusions We report a pleiotropic locus between SSc and lung cancer, illuminating potential pathobiological mechanisms and providing gene candidates for future research.

PLOS ONE

Performance optimization design for constructed wetland coupled with microbial fuel cell for rural domestic sewage treatment

by Tuodi Zhang, Songtao Shen, Yingyi Xu A vertical-flow constructed wetland-microbial fuel cell (CW-MFC) was established with Acorus calamus as the wetland vegetation for rural domestic wastewater treatment under low-temperature winter conditions. Response surface methodology (RSM) coupled with central composite design (CCD) was used to optimize three key electrode parameters: electrode plate projection coefficient (PC), inter-electrode distance (ID), and external resistance (ER), and to evaluate their effects on COD removal efficiency. Compared with the standalone constructed wetland (CW), the CW-MFC system significantly improved wastewater treatment performance: the effluent COD concentration of the CW was 66.14 mg/L, exceeding the first-class discharge limit (60.00 mg/L) specified in the “Water Pollutant Discharge Standard for Rural Domestic Sewage Treatment Facilities” (DB51/2626–2019). In contrast, the effluent COD concentrations of the CW-MFC system ranged from 18.81 to 54.06 mg/L, all meeting the aforementioned first-class standard, with a significantly higher COD removal rate than the CW (P < 0.05). After electrode parameter optimization, the optimal configuration was determined as PC = 0.33, ID = 272.94 mm, and ER = 1619.31 Ω. Under these optimized conditions, the CW-MFC system achieved a COD removal efficiency of 89.14%, which was consistent with the model-predicted value (88.06%) with a deviation of <1.2%. This confirmed that electrode parameter optimization effectively enhanced the treatment performance of the CW-MFC system. These findings could contribute new perspectives to the performance optimization of CW-MFC systems applied to decentralized rural domestic sewage treatment, particularly under low-temperature winter scenarios.

PLOS ONE

Serum ferritin in Yemeni patients with sickle cell anemia: Association with sociodemographic factors and hematological profiles

by Abdulsalam Al-Shami, Lutfi A. S. Al-Maktari, Lina Qasem, Khalid Aldhorae, Shimaa AL-Khaship Background Iron overload remains a critical complication secondary to transfusional therapy and altered iron metabolism in patients with sickle cell anemia (SCA). Hyperferritinemia often serves as a surrogate marker for iron overload; however, as an acute-phase reactant, it may be elevated due to chronic inflammation, infection, or liver disease, potentially overestimating true iron stores. In Yemen, the burden of SCA is high, yet local data on the frequency of hyperferritinemia are scarce. This study aimed to describe the distribution of serum ferritin (SF) levels and the proportion of SCA patients with hyperferritinemia among adolescents and young adults attending the YSTH clinic in Sana’a, and to explore associations with hematological, and sociodemographic parameters. Methods A prospective cross-sectional study was conducted between June and December 2024, involving 80 participants (aged ≥ 15 years). The data were analyzed using SPSS version 26. Due to the non-normal distribution and high dispersion of SF, the Median (IQR) and Spearman correlation were utilized. Bivariate analysis calculated crude odds ratio at (95% CI) to identify predictor of elevated SF. Statistical power was limited by the sample size (N = 80) to detect weak associations. Results The study enrolled 80 SCA patients with a mean (±SD) age of 18.5 (±3.69) years, of whom 65% were males and 35% were females. The median (IQR) SF level was 1645 ng/mL (414–3525), with values ranging from 77.1 to 4500.0 ng/mL. Approximately 85% of patients exhibited elevated SF level (≥300 ng/mL). While red cell indices did not significantly predict the risk of hyperferritinemia, a significant positive correlation was observed between SF levels and white blood cell count (p = 0.03), suggesting a possible link with the inflammatory state. No significant associations were found between sociodemographic factors and high SF levels. Conclusion A high prevalence (85%) of hyperferritinemia (≥ 300 ng/mL) was observed among SCA patients attending the YSTH in Sana’a, Yemen, suggesting probable iron overload. While findings support routine SF screening but highlight the need for future studies incorporating inflammatory markers (e.g., CRP) and systematic transfusion histories to definitively quantify the iron overload burden in this population.

PLOS ONE

Barriers and facilitators to implementing childcare in long-term care homes: A scoping review protocol and consultative exercise

by Kristina M. Kokorelias, Annie Robitaille Background Long-term care (LTC) homes face persistent workforce recruitment and retention challenges, particularly among staff balancing professional responsibilities with childcare needs. Integrating childcare services within LTC homes has the potential to improve staff well-being, workforce stability, and resident experiences through intergenerational engagement. Despite this potential, the implementation literature remains fragmented, and no systematic synthesis of barriers, facilitators, or contextual determinants exists. Objective To systematically map the literature on barriers and facilitators to implementing childcare services within LTC homes and identify gaps to inform research, policy, and practice. Methods We will conduct a scoping review following the Arksey and O’Malley framework, enhanced by Levac et al., and report findings according to PRISMA-P and PRISMA-ScR guidelines. Literature searches will be conducted in MEDLINE, CINAHL, Embase, Scopus, and PsycINFO, supplemented by grey literature searches. Eligible studies include qualitative, quantitative, or mixed-methods research, program evaluations, and policy reports examining implementation of childcare services within or linked to LTC homes. Two reviewers will independently screen studies, extract data using a standardized form, and resolve discrepancies through discussion or a third reviewer. Extraction will capture study characteristics, childcare model details, reported barriers and facilitators, and outcomes. Findings will be synthesized narratively and organized thematically using the Consolidated Framework for Implementation Research (CFIR 2.0). Stakeholder engagement with LTC and early childhood centre staff will guide interpretation and knowledge translation. Expected outcomes The review will identify key determinants of successful implementation, highlight gaps in the evidence, and provide actionable insights for LTC administrators, early childhood partners, and policymakers seeking to develop sustainable, equitable co-located childcare programs that benefit residents, children, and staff.

PLOS ONE

Comparison of scenario reduction approaches for reservoir inflow timeseries generated by a Bayesian Neural Network

by Ja-Ho Koo, Edo Abraham, Andreja Jonoski, Dimitri P. Solomatine Dealing with uncertainty in predicted inflows presents a major challenge in optimal reservoir flood control. Scenario-based stochastic control approaches address this by generating multiple inflow time series from probabilistic models, each representing a possible future with associated likelihoods. However, using too many scenarios increases computational complexity, while too few may compromise representativeness. Although the two critical steps of scenario generation and reduction have been extensively explored in other fields, their application to reservoir inflow dynamics remains limited. This study develops and applies a probabilistic data-driven model, specifically, a Bayesian Neural Network (BNN), for scenario generation. While the model exhibits limitations in predicting peak inflows due to data scarcity, it effectively captures temporal dependencies in inflow time series and achieves high short-term accuracy, as measured by the Nash–Sutcliffe Efficiency Coefficient (NSE) and Root Mean Squared Error (RMSE), though performance declines over longer horizons. For scenario reduction, four distance measures widely used in other domains, i.e., the Manhattan, Euclidean, Wasserstein, and energy distances, are evaluated. Experimental results show that the energy distance best preserves the statistical properties of the full scenario set, followed by the Manhattan and Euclidean distances. However, in terms of retaining extreme inflow scenarios, which are critical for flood control, the Manhattan and Euclidean distances outperform others based on a custom index measuring the envelope size of the original scenario set using the l1-norm. In terms of computational efficiency of scenario reduction approaches, the energy distance is the most expensive (quadratic in m, the number of reduced scenarios), while the Wasserstein scales linearly. In the examples used, reduced sets are shown to adequately capture extremes when the number of scenarios m ≥ 30. Considering the trade-off between preserving extremes and computational cost, the Manhattan and Euclidean distances with m = 30 are recommended as a practical choice for reservoir inflow scenario reduction.

PLOS ONE

Seismic fragility analysis of fully prefabricated frame structures with steel plate hoop bolt connections based on various engineering demand parameters

by Zhiyuan Gao, Jiaolei Zhang, Lei Cao Steel plates and bolted connections have become common construction details in prefabricated structural systems. However, prefabricated frame structures with steel plate hoop–bolted connections exhibit connection gaps, interface slip, and discontinuous force-transfer paths, making them prone to hysteretic degradation and cumulative damage under seismic loading. Conventional seismic fragility assessments typically rely on the maximum inter-story drift ratio, which focuses only on deformation demand and fails to capture key deterioration mechanisms such as low-cycle damage accumulation, stiffness degradation, and reduced energy dissipation capacity. Consequently, the seismic performance of prefabricated structures may be inadequately represented. To address this limitation, this study adopts a two-parameter damage model as the engineering demand parameter for incremental dynamic analysis (IDA) and fragility assessment, and compares it with the traditional drift-based index. An energy-dissipation-based story damage weighting method is further introduced to better characterize damage distribution and performance degradation along the structural height. Finite element models of prefabricated columns and beam–column joints with steel plate hoop–bolted connections were developed in SAP2000 using multilinear plastic link elements and validated against quasi-static test results. A comparative fragility analysis was then performed for six-story full prefabricated and cast-in-place frame structures. The results show that the inter-story drift ratio underestimates structural capacity in the elastic stage but overestimates collapse resistance compared with the two-parameter damage model.

PLOS ONE

Early treatment interruption and nutritional status as predictors of mortality in <i>Mycobacterium avium</i> complex pulmonary disease

by Hye Young Hong, Youngmok Park, Song Yee Kim, A La Woo, Hye-Jeong Lee, Young Ae Kang Mycobacterium avium complex pulmonary disease (MAC-PD) requires prolonged multidrug therapy. However, treatment outcomes remain suboptimal due to limited antibiotic efficacy, disease chronicity, and frequent early treatment interruption (ETI). Despite its clinical significance, data on the prevalence, risk factors, and long-term outcomes of ETI remain limited. Therefore, this study aims to identify factors associated with ETI and its impact on mortality. A retrospective cohort study of 420 patients treated with MAC-PD was conducted between 2010 and 2023. Patients were categorized into ETI (treatment duration < 12 months) and standard groups (treatment duration ≥ 12 months). Logistic regression was used to identify risk factors for ETI, whereas multivariate Cox proportional hazards regression was employed to evaluate factors associated with mortality. ETI occurred in 30% of patients. Low prognostic nutritional index (PNI) (adjusted odds ratio [aOR]: 0.92; 95% confidence Interval [CI]: 0.87–0.99) and grade 2 or higher adverse drug reactions (ADRs) (aOR: 5.65; 95% CI: 2.45–15.00) increased the risk of ETI. ETI was associated with higher mortality (adjusted hazard ratio: 2.86; 95% CI: 1.51–5.40). Additionally, low PNI scores indicated increased mortality risk. ETI is prevalent in MAC-PD and is strongly associated with ADRs and poor nutrition, both of which also predict higher long-term mortality. Early ADR monitoring and nutritional support are essential for improving treatment adherence and patient outcomes.

PLOS ONE

Exploring the perceived impact of physical activity on physical and mental health among individuals with long COVID: A qualitative interview inquiry

by Zoe Sirotiak, Ann M. Oberhauser, Arie M. Sirotiak, Kate A. Nettleton, Duck-chul Lee, Emily B. K. Thomas, Angelique G. Brellenthin Objectives Long COVID presents a significant health burden with limited treatment options. Physical activity (PA) has been suggested for self-management, yet symptom worsening has been reported in similar patient populations. This study aims to identify PA’s perceived impact on physical and mental health in adults with long COVID. Methods Semi-structured interviews were conducted with 34 adults (mean age 52 years, 62% women) based in the United States (U.S.) self-reporting long COVID. PA-related content was analyzed using deductive thematic analysis, assessing worsened and improved health experiences attributed to PA. Results Participants’ perceived health scores were one standard deviation worse than the general U.S. population. Most participants (64.7%) reported worsening long COVID symptoms with PA, while 14.7% noted improvement. Themes for worsened physical health included post-exertional malaise, specific symptom worsening (e.g., fatigue), limited PA abilities, external control perceptions, forced inactivity, and loss of previous PA abilities. Improved health themes involved beliefs in health benefits, symptom improvement, increased energy, accomplishment, enhanced PA abilities, and hope. Discussion PA’s impact on health varied among individuals with long COVID, highlighting the need to tailor PA recommendations to individual needs and limits.

PLOS ONE

Vocational rehabilitation for people with multiple sclerosis: A systematic scoping review of international evidence

by Carlotta Gualco, Erica Grange, Federica Rotondi, Marco Salivetto, Elena Pignattelli, Tommaso Manacorda, Maria Grazia Grasso, Giorgia Presicce, Matilde Inglese, Lorenza Nasone, Paolo Durando, Guglielmo Dini, Benedetta Persechino, Giampaolo Brichetto, Michela Ponzio Introduction People with multiple sclerosis (pwMS) may encounter challenges in their professional lives, due to a combination of environmental and individual factors. According to Escorpizo et al., 2011 framework, Vocational rehabilitation (VR) aims to optimise job participation, providing support in the job access, retention and in the return to work for people with disability. However, the corpus of research on VR for pwMS is poor. This scoping review aims to map the available literature on VR interventions for pwMS, summarising their characteristics, study designs, implementation features, feasibility, and stakeholders’ perspectives. Methods Following the Joanna Briggs Institute (JBI) and the PRISMA-ScR guidelines, seven databases were searched up to October 2025: PubMed, SCOPUS, PsycInfo, CINAHL, Google Scholar, OT Seeker (University of Queensland), and the Physiotherapy Evidence Database (PEDro). Studies were eligible if they were related to VR interventions for pwMS, focused on job access, return, or retention and if they were primary articles. Data were extracted and synthesised following the Population–Concept–Context (PCC) framework. Results Out of 2,360 records, 28 articles describing 28 distinct VR interventions were included. Studies were published between 1996 and 2025, mostly from Western countries. Designs ranged from descriptive to randomized trials, with an increasing number of interventional and feasibility studies in recent years. The 61% of the interventions were multi-dimensional delivering a combination of rehabilitation, educational, and reasonable accommodation services. PwMS highlighted the importance of empathetic and individualized approaches, symptom management, and legal counselling as key elements in VR interventions, while logistical, personal and health issues were barriers to participation. Overall, interventions were considered feasible and acceptable. Conclusions This is the first comprehensive overview of VR interventions for pwMS, outlining a progressive shift toward multidisciplinary and goal-oriented approaches over time. Despite promising feasibility and stakeholder satisfaction, further rigorous trials are needed to evaluate effectiveness and inform evidence-based implementation of VR programmes in diverse contexts.

PLOS ONE

The impact of university students’ computational thinking on AI literacy: A longitudinal study based on SEM-PLS

by Qiuyu Li, Tinglan Huang, Lehui Huang, Xueshi Wu Artificial intelligence literacy is a core competency that underpins individual development. Although previous studies have demonstrated a cross-sectional association between computational thinking and artificial intelligence literacy, there has been little analysis of their longitudinal effects. This study utilized a sample of 216 undergraduate students from southern China and employed structural equation modeling (SEM-PLS) and paired-sample t-tests. Through a two-stage longitudinal data analysis, the study found that computational thinking has a significant positive effect on artificial intelligence literacy and that both competencies improved significantly over time. By tracking the evolution of these two competencies, this study offers a novel longitudinal perspective, confirms their synchronous development, and highlights the stability of their cross-sectional relationship, thereby providing theoretical foundations and methodological references for educational practice.

PLOS ONE

Beyond diagonal noise: A better predator-prey modeling framework with cross-covariance

by Jiguang Yu, Louis Shuo Wang The introduction of stochasticity into continuous ecological models frequently relies on phenomenological, diagonal diffusion terms that lack a rigorous microscopic basis. We demonstrate that this standard practice fundamentally misrepresents the geometry of demographic fluctuations. By deriving a stochastic Rosenzweig–MacArthur model directly from an integer-valued, Bernoulli-coupled continuous-time Markov chain, we isolate the exact diffusion covariance structure dictated by event stoichiometry. We mathematically prove that coupled predation–conversion events inherently generate a structurally negative predator–prey cross-covariance, exposing the severe mathematical and biological limitations of standard diagonal-noise approximations. Furthermore, we resolve a persistent ambiguity in stochastic population modeling by explicitly formalizing the bifurcation between open-domain formulations (for survival-conditioned interior dynamics) and absorbed formulations (for extinction-permitting dynamics). To rigorously support this distinction, we develop a tailored two-stage Lyapunov well-posedness architecture that separates non-explosion criteria from boundary-barrier positivity invariance. By bridging microscopic event stoichiometry with macroscopic boundary-degenerate diffusions, this work replaces ad hoc noise constructs with a definitive, mathematically exact template for covariance-consistent and boundary-aware ecological modeling.

PLOS ONE

Correction: Megakaryocytic Leukemia 1 (MKL1) Regulates Hypoxia Induced Pulmonary Hypertension in Rats

by Zhibin Yuan, Jian Chen, Dewei Chen, Gang Xu, Minjie Xia, Yong Xu, Yuqi Gao

PLOS ONE

Archaeomagnetic evidence indicates post-Inka reheating of metallurgical kilns at Quillay (NW Argentina)

by Judit del Río, Miriam Gómez-Paccard, Alicia Palencia-Ortas, Annick Chauvin, Mara Basile, Norma Ratto, Pablo Cruz, Marco Antonio Giovannetti This study presents an archaeomagnetic analysis of five metallurgical kilns from the settlement of Quillay (Catamarca, NW Argentina), attributed to the Inka period on the basis of radiocarbon dates and archaeological evidence. All five structures yielded consistent paleofield values, and directional and intensity determinations are statistically indistinguishable which suggests that the sampled parts of the kilns were reheated within a relatively short interval. Comparison with geomagnetic field models, particularly BIGMUDI4k.1, indicates that this last heating event occurred between the late nineteenth and mid-twentieth centuries, rather than during the Inka occupation. The discrepancy between the archaeomagnetic and radiocarbon evidence is therefore consistent with a later remagnetization event affecting the structures. Possible explanations include a local wildfire or the deliberate re-use of the upper chambers to recover copper from slag. The results refine our knowledge about the occupational history of Quillay, and support the interpretation of a later thermal event affecting structures originally used in Inka times.

PLOS ONE

HIV/AIDS burden, attributable risk factors, and projections among reproductive-age adults in China, 1990–2035: A GBD 2023 analysis

by Huibo Yan Background HIV/AIDS remains a leading infectious disease burden globally. While highly active antiretroviral therapy has transformed HIV into a manageable chronic condition, contemporary trends and attributable risk factors among reproductive-age adults in China—a critical demographic for epidemic control—remain poorly characterized. This study provides an updated comprehensive assessment of HIV/AIDS burden in this population using Global Burden of Disease Study 2023 data, which incorporates methodological refinements and post-pandemic data not available in earlier versions. Methods We extracted age-standardised incidence, prevalence, mortality and disability-adjusted life-years (DALYs) for Chinese adults aged 15–49 years from GBD 2023. Joinpoint regression estimated annual percent change and identified significant trend inflection points. Population attributable fractions were analysed for unsafe sex, drug use, and intimate-partner violence. ARIMA models forecasted burden trends to 2035 with 95% uncertainty intervals. Results Between 1990 and 2023, age-standardised rates increased substantially: incidence +301% (from 0.82 to 3.29 per 100,000), prevalence +774% (4.84 to 42.29), mortality +1,623% (0.13 to 2.24), and DALYs + 1,439% (7.96 to 122.48). Males showed consistently steeper increases than females across all metrics (all p < 0.05). Unsafe sex accounted for 70% of HIV/AIDS mortality in 2023. ARIMA projections indicate that while male incidence will plateau at ~5.0 per 100,000 by 2035, female metrics will continue rising (incidence +21%, prevalence +30%), widening the sex disparity. Conclusion China’s HIV epidemic has transitioned to a chronic disease burden. Notably, this burden shows pronounced sex differences. Mortality is rising among people living with HIV, particularly among women. These trends highlight urgent needs for gender-differentiated prevention strategies. Our findings provide measurable targets for China’s National HIV/AIDS Action Plan (2024–2030) and SDG 3.3 monitoring. They further demonstrate how standardized burden estimation supports precision public health.

PLOS ONE

Expression of Concern: Development of innovative alkali activated paste reinforced with polyethylene fibers for concrete crack repair

by The PLOS One Editors

PLOS ONE

Editorial Note: Host-Associated Metagenomics: A Guide to Generating Infectious RNA Viromes

by The PLOS One Editors

PLOS ONE

Correction: Predicting the unpredicted … brain response: A systematic review of the feature-related visual mismatch negativity (vMMN) and the experimental parameters that affect it

by The PLOS One Editors

PLOS ONE

Expression of Concern: BlockTicket: A framework for electronic tickets based on smart contract

by The PLOS One Editors

PLOS ONE

Correction: The effect of Moringa oleifera capsule in increasing breastmilk volume in early postpartum patients: A double-blind, randomized controlled trial

by The PLOS One Editors

← 이전21 / 23다음 →