New experimental approach may help overcome drug resistance in deadly brain cancer

Scientists have identified a promising new strategy to tackle one of the biggest obstacles in treating glioblastoma, one of the most aggressive forms of brain cancer: resistance to chemotherapy.

The study shows that an experimental compound called BA-101 can restore the effectiveness of the standard drug temozolomide (TMZ) by blocking a biological process known as nitrosative stress, which helps tumors survive and resist treatment. ...