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Federal Register Notices
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Pesticide Product Registration; Receipt of Applications for New Active Ingredients (March 2026)

Federal Register Notices
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This site displays a prototype of a “Web 2.0” version of the daily Federal Register. It is not an official legal edition of the Federal Register, and does not replace the official print version or the official electronic version on GPO’s govinfo.gov. The documents posted on this site are XML renditions of published Federal Register documents. Each document posted on the site includes a link to the corresponding official PDF file on govinfo.gov. This prototype edition of the daily Federal Register on FederalRegister.gov will remain an unofficial informational resource until the Administrative Committee of the Federal Register (ACFR) issues a regulation granting it official legal status. For complete information about, and access to, our official publications and services, go to About the Federal Register on NARA's archives.gov. The OFR/GPO partnership is committed to presenting accurate and reliable regulatory information on FederalRegister.gov with the objective of establishing the XML-based Federal Register as an ACFR-sanctioned publication in the future. While every effort has been made to ensure that the material on FederalRegister.gov is accurately displayed, consistent with the official SGML-based PDF version on govinfo.gov, those relying on it for legal research should verify their results against an official edition of the Federal Register. Until the ACFR grants it official status, the XML rendition of the daily Federal Register on FederalRegister.gov does not provide legal notice to the public or judicial notice to the courts. Notice Enter a search term or FR citation e.g. 88 FR 38230 FR 78782024-13208USDA09/05/24RULE0503-AA39SORN Choosing an item from full text search results will bring you to those results. Pressing enter in the search box will also bring you to search results. Choosing an item from suggestions will bring you directly to the content. Thank you for taking the time to create a comment. Your input is important. Once you have filled in the required fields below you can preview and/or submit your comment to the Environmental Protection Agency for review. All comments are considered public and will be posted online once the Environmental Protection Agency has reviewed them. Comments must be received on or before July 22, 2026. Table of Contents Enhanced Content - Table of Contents This table of contents is a navigational tool, processed from the headings within the legal text of Federal Register documents. This repetition of headings to form internal navigation links has no substantive legal effect. Document page views are updated periodically throughout the day and are cumulative counts for this document. Counts are subject to sampling, reprocessing and revision (up or down) throughout the day. Page views 0 as of 06/20/2026 at 12:15 am EDT Other Formats Enhanced Content - Other Formats This document is also available in the following formats: This PDF is FR Doc. 2026-12418 as it appeared on Public Inspection on 06/18/2026 at 8:45 am. It was viewed 17 times while on Public Inspection. If you are using public inspection listings for legal research, you should verify the contents of the documents against a final, official edition of the Federal Register. Only official editions of the Federal Register provide legal notice of publication to the public and judicial notice to the courts under 44 U.S.C. 1503 & 1507. Learn more here. Published Document: 2026-12418 (91 FR 37111) This document has been published in the Federal Register. Use the PDF linked in the document sidebar for the official electronic format. AGENCY: Environmental Protection Agency (EPA). ACTION: Notice of receipt and request for comment. SUMMARY: This document announces the Agency's receipt of and solicits comments on applications to register pesticide products containing active ingredients not included in any currently registered pesticide products. The Agency is providing this notice in accordance with the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). EPA uses the month and year in the title to identify when the Agency complied with the applications identified in this notice of receipt. Unit II. of this document identifies certain applications received in 2024 and 2025 that are currently being evaluated by EPA, along with information about each application, including when it was received, who submitted the application, and the purpose of the application. DATES: Comments must be received on or before July 22, 2026. ADDRESSES: Submit your comments, identified by the docket identification (ID) number and the EPA File Symbol or the EPA Registration Number of interest as shown in Unit II. of this document, online at https://www.regulations.gov. Follow the online instructions for submitting comments. Do not submit electronically any information you consider to be Confidential Business Information (CBI) or other information whose disclosure is restricted by statute. Additional instructions on commenting on and visiting the docket, along with more information about dockets generally, are available at https://www.epa.gov/dockets. FOR FURTHER INFORMATION CONTACT: Each application summary in Unit II. specifies a contact division. The appropriate division contacts are identified as follows: BPPD (Biopesticides and Pollution Prevention Division) (Mail Code 7511M); Alan Reynolds; main telephone number: (202) 566-1471; email address:BPPDFRNotices@epa.gov. SUPPLEMENTARY INFORMATION: ( printed page 37112) I. Executive Summary A. Does this action apply to me? This action provides information that is directed to the public in general. B. What is the Agency's authority for taking this action? EPA is taking this action pursuant to section 3(c)(4) of the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), 7 U.S.C. 136a(c)(4), and 40 CFR 152.102. C. What action is the Agency taking? EPA is hereby providing notice of receipt and opportunity to comment on applications to register pesticide products containing active ingredients not included in any currently registered pesticide products. Notice of receipt of these applications does not imply a decision by the Agency on these applications. The applications identified in this document were received since the last notice that was issued and are currently being evaluated by EPA in accordance with the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). For actions being evaluated under EPA's public participation process for registration actions, there will be an additional opportunity for public comment on the proposed decisions. Please see EPA's public participation website for additional information on this process ( https://www.epa.gov/registration/participation-process-registration-actions). D. What should I consider as I prepare my comments for EPA? 1. Submitting CBI. Do not submit CBI to EPA through https://www.regulations.gov or email. If you wish to include CBI in your comment, please follow the applicable instructions at https://www.epa.gov/dockets/commenting-epa-dockets#rules and clearly mark the information that you claim to be CBI. In addition to one complete version of the comment that includes CBI, a copy of the comment without CBI must be submitted for inclusion in the public docket. Information marked as CBI will not be disclosed except in accordance with procedures set forth in 40 CFR part 2. This unit provides the following information about the applications received: The EPA File Symbol or Registration number(s); EPA docket ID number for the application; Name and address of the applicant; Name of the active ingredient, product type and proposed uses; and the division to contact for that application. Additional information about the application may also be available in the docket for the application as identified in this unit. EPA File Symbol: 82398-E. Docket ID number: EPA-HQ-OPP-2025-0113. Applicant: Chemian Technology Limited, Unit 2, 80 Eastmount Road, Darlington, County Durham, DL1 1LA, United Kingdom c/o TSG Consulting, 1150 18th Street NW, Suite 475, Washington, DC 20036. Product name: Citrepel 75. Active ingredient: Cymbopogon winterianus oil, fractionated, hydrated, cyclized; cymbopogon winterianus oil, fractionated, hydrated, cyclized at 100.00%. Proposed classification/use: Manufacturing Use Product. Date of receipt: February 22, 2024. Contact: BPPD. EPA File Symbol: 82398-G. Docket ID number: EPA-HQ-OPP-2025-0113. Applicant: Chemian Technology Limited, Unit 2, 80 Eastmount Road, Darlington, County Durham, DL1 1LA, United Kingdom c/o TSG Consulting, 1150 18th Street NW, Suite 475, Washington, DC 20036. Product name: Citrepel Emulsion 20 Insect Repellent. Active ingredient: Cymbopogon winterianus oil, fractionated, hydrated, cyclized; cymbopogon winterianus oil, fractionated, hydrated, cyclized at 20.00%. Proposed classification/use: End Use Product- Skin applied Insect Repellent. Date of receipt: February 22, 2024. Contact: BPPD. EPA File Symbol: 82398-U. Docket ID number: EPA-HQ-OPP-2025-0113. Applicant: Chemian Technology Limited, Unit 2, 80 Eastmount Road, Darlington, County Durham, DL1 1LA, United Kingdom c/o TSG Consulting, 1150 18th Street NW, Suite 475, Washington, DC 20036. Product name: Incognito Insect Repellent. Active ingredient: Cymbopogon winterianus oil, fractionated, hydrated, cyclized; cymbopogon winterianus oil, fractionated, hydrated, cyclized at 20.00%. Proposed classification/use: End Use Product- Skin applied Insect Repellent. Date of receipt: February 22, 2024. Contact: BPPD. EPA File Symbol: 90866-UG. Docket ID number: EPA-HQ-OPP-2026-2740. Applicant: CH Biotech R&D Co., c/o CH Biotech LLC, 601 Kettering Drive, Ontario, CA 91761. Product name: Melatonin Technical. Active ingredient: Melatonin; Melatonin at 99.7%. Proposed classification/Use: Manufacturing Use Product. Date of receipt: March 29, 2024. Contact: BPPD. EPA File Symbol: 90866-UE. Docket ID number: EPA-HQ-OPP-2026-2740. Applicant: CH Biotech R&D Co., c/o CH Biotech LLC, 601 Kettering Drive, Ontario, CA 91761. Product name: CHB-ST (GIM). Active ingredient: Melatonin; Melatonin at 1.0%. Proposed classification/use: Seed Treatment. Date of Receipt: March 29, 2024. Contact: BPPD. EPA File Symbol: 90866-UR. Docket ID number: EPA-HQ-OPP-2026-2740. Applicant: CH Biotech R&D Co., c/o CH Biotech LLC, 601 Kettering Drive, Ontario, CA 91761. Product name: CHB-FNA. Active ingredient: Melatonin; Melatonin at 1.0%. Proposed classification/use: Plant Growth Regulator. Date of receipt: March 29, 2024. Contact: BPPD. EPA File Symbol: 100975-E. Docket ID number: EPA-HQ-OPP-2026-2411. Applicant: Ascribe Bioscience, Inc, 95 Brown Rd., Suite 202, Ithaca, NY 14850 (c/o SciReg, Inc., 12733 Director's Loop, Woodbridge, VA 22192. Product name: Phytalix. Active ingredient: (10R)-10-[(2R,3R,5R,6S)-3,5-dihydroxy-6-methyloxan-2-yl] oxyundecanoic acid (Ascr#18); (10R)-10-[(2R,3R,5R,6S)-3,5-dihydroxy-6-methyloxan-2-yl] oxyundecanoic acid (Ascr#18) at 0.042%. Proposed classification/use: Ascarosides. For use on-farm, greenhouse, and commercial foliar and seed treatment for activation of plant defense against fungal, viral, and bacterial pathogens. Date of receipt: February 15, 2024. Contact: BPPD. EPA File Symbol: 100975-R. Docket ID number: EPA-HQ-OPP-2026-2411. Applicant: Ascribe Bioscience, Inc, 95 Brown Rd., Suite 202, Ithaca, NY 14850 (c/o SciReg, Inc., 12733 Director's Loop, Woodbridge, VA 22192. Product name: ASCR #18 Technical. Active ingredient: (10R)-10-[(2R,3R,5R,6S)-3,5-dihydroxy-6-methyloxan-2-yl] oxyundecanoic acid (Ascr#18), Ascarosides; (10R)-10-[(2R,3R,5R,6S)-3,5-dihydroxy-6-methyloxan-2-yl] oxyundecanoic acid (Ascr#18) at 95.24%. Proposed classification/use: Manufacturing Use product (MP). Date of receipt: February 15, 2024. Contact: BPPD. EPA File Symbol: 104223-R. Docket ID number: EPA-HQ-OPP-2026-2510. Applicant: Agragene, Inc., 11861 Westline Industrial Drive, Suite 800, St. Louis, MO 63146. Product name: KNOCKOUT SWD. Active ingredient: A complex consisting of loss of function edits to βtub2 and sxl genes, gRNA, and the SpCas9 protein. Proposed use: Insecticide. Date of receipt: August 6, 2025. Contact: BPPD.
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Pesticide Product Registration; Receipt of Applications for New Active Ingredients (March 2026)