Neurobiologists improve symptoms of Huntington's disease with targeted brain stimulation in mice

Huntington's disease is a devastating brain disorder in which decaying nerve cells lead to progressively worsening cognitive and movement abilities.

While the genetic mutation responsible for the condition is well known, the intricate details of how the disease disrupts specific brain circuits have not been clearly understood.

This gap has complicated efforts to develop effective therapies, and the disease remains fatal, with no known cure. ...