Clarifying the interplay between host and gut microbiota in selenium metabolism

Selenium (Se) is an essential trace mineral found in everyday dietary items, such as seafood, meat, and whole grains.

Our bodies depend on it for many biological functions, from the synthesis of antioxidant enzymes to immune system regulation.

However, Se is unusual among nutrients in that the quantity window between too little and too much is quite narrow.

Se deficiency has been linked to weakened immunity, while excess intake can increase the risk of type 2 diabetes and cardiovascular disorders.

This makes understanding how the body absorbs, processes, and eliminates Se especially important. ...