Researchers develop chimeric allergen receptors as a new immunotherapy approach for asthma

Genetically engineered CAR T cells expressing artificial receptor proteins are increasingly used in the clinic to boost the immune system's response against leukemias and other cancers.

In a study published in the Journal of Experimental Medicine (JEM), researchers in Switzerland have adapted this approach to suppress the immune system's response to a common allergen, reducing or preventing asthma symptoms in mice.

The technique could eventually be used to treat a wide variety of allergies in humans. ...