Psychedelic drug screen in mice may overlook stress and brain changes

Over the past decades, some medical researchers and neuroscientists have been exploring the possible therapeutic effects of psychedelic compounds, such as lysergic acid diethylamide (LSD) and psilocybin.

These are substances that act on serotonin receptors in the brain and can alter people's perceptions, mood and mental processes.

Some preliminary studies suggest that they could help treat specific psychiatric conditions, such as major depression and post-traumatic stress disorder (PTSD).

Nonetheless, psychedelics also prompt hallucinations, distorted perceptions and heightened emotions, which can be distressing and unfavorable for many psychiatric patients. ...