MetaCaDI: A Meta-Learning Framework for Causal Discovery from Multiple Environments with Unknown Interventions

Uncovering the causal mechanisms of complex real-world systems remains a significant challenge, as these systems often entail high data collection costs and involve unknown interventions.

We introduce MetaCaDI, the first framework to cast the identification of unknown interventions as a meta-learning problem, explicitly leveraging a jointly learned causal graph.

MetaCaDI is a Bayesian framework that learns a shared causal structure across multiple environments and is optimized to rapidly adapt to new, few-shot intervention target identification tasks.

A key innovation is our model's analytical adaptation, which uses a closed-form solution to bypass expensive and potentially unstable gradient-based bilevel optimization.

Extensive experiments on synthetic and complex gene expression data demonstrate that MetaCaDI significantly outperforms state-of-the-art methods.

It excels at identifying intervention targets from as few as 3 samples - where existing methods collapse to random chance - while robustly recovering the shared causal graph, proving its effectiveness in data-scarce scenarios.