Microglia mechanism reveals why brain's stroke repair window closes

Stroke is one of the leading causes of long-term disability worldwide and often results in impairments in movement, speech and cognition.

While rehabilitation helps patients regain some lost functions, the brain's natural ability to repair itself often fades within a few months after an injury.

This limited period of spontaneous recovery poses a major challenge for patients, often resulting in permanent neurological deficits after the brain's intrinsic repair capacity declines. ...