Scientists say creatine may help fight depression

Creatine is best known as a muscle-building supplement, but scientists are now investigating whether it could also help treat depression by boosting the brain's energy supply.

A new review examined five randomized clinical trials involving 238 participants and found mixed results.

Two studies, both involving women with major depressive disorder, reported that adding creatine to standard treatment improved symptoms, while three others found no meaningful benefit. ...