Mitochondria reveal new TDP-43 signaling route tied to ALS and dementia

A new study published in Nature Communications has uncovered a communication pathway between mitochondria and RNA granules that may help scientists understand how the toxic buildup of the TDP-43 protein leads to the development of certain neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). ...