Toward a local manipulation of DNA by quantum fields
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Abstract
Hydrogen bonds are the fundamental backbone for deoxyribo-nucleic acid (DNA) stability.
In this letter we propose a new strategy based on plasmonic cavities to perform a local manipulation of hydrogen bonds in DNA.
The analysis is performed using state-of-the-art Quantum Electrodynamics Coupled Cluster calculations (QED-CC).
We demonstrate that in standard strong coupling regimes, small but appreciable local modifications of the nucleotide bases' interactions can be induced in a totally non-intrusive manner.
The effect can eventually be enhanced if ultra-strong coupling conditions can be reached.
Our strategy provides an alternative approach to methodologies based on a collective coupling to perform optical DNA manipulation.