Scientists engineer personalized cartilage graft for infants with life-threatening airway narrowing

A study led by researchers at Children's Hospital of Philadelphia (CHOP) demonstrates a new method of using decellularized cartilage with patient-specific cells to help enlarge pediatric airways narrowed as a result of severe subglottic stenosis.

Researchers demonstrate that this new method is faster, more effective and able to overcome issues associated with the current standard grafts, such as donor site morbidity, insufficient tissue volume and a delayed timeline.

The findings are published in the journal Nature Communications. ...