Drug candidate could help L-dopa work better for patients with Parkinson's

For many people with Parkinson's disease, the body stops moving the way it used to.

A hand may tremble at rest.

Muscles may stiffen.

Walking can become slower and balance more uncertain.

The most effective treatment remains L-dopa, also called levodopa, a medication that can dramatically improve movement and quality of life.

But the relief often comes with a caveat: Over time, the drug's benefits can become less reliable, and it can cause erratic, involuntary movements known as dyskinesia. ...