First large-scale atlas of senescent cells could help inform future therapies for age-related diseases

A research consortium has established a new framework to identify and catalog senescent cells—cells that stop dividing but remain active in the body.

Because senescent cells accumulate with age and are thought to contribute to many age-related conditions, researchers are working to better understand the roles they play in health and disease.

In a compendium of papers published by Cell Press, the consortium presents the first comprehensive atlas of senescent cells across the human body, a foundational step toward developing new therapies for age-related diseases. ...