Topology of the Set of Entangled State

We investigate the topology of the set $\mathsf E$ of entangled bipartite density operators acting on $\mathbb{C}^{n_1}\otimes\mathbb{C}^{n_2}$. We start by showing that $\mathsf E$ is path-connected, and even simply connected except in the two-qubit case. In this exceptional case $\mathsf E$ turns out to be homotopy equivalent to the set of maximally entangled states, which itself is homeomorphic to $\mathbb{RP}^3$. Here we also compute the complete homology of the closure and interior of $\mathsf E$.
In all larger dimensions, we show that the homology and homotopy groups of $\mathsf E$ vanish in degrees $1\leq k\leq 2(n_1-1)(n_2-1)-2$, and all homology groups of degree $k\geq (n_1n_2)^2-3$ also vanish. This range is controlled by the space $\mathsf W$ of entanglement witnesses, which we show is highly connected beyond two qubits and homotopy equivalent to $\mathsf E$. By computing the Euler characteristic, using a torus-action fixed point argument together with Alexander duality, we show that $\mathsf E$ nevertheless has non-trivial reduced homology over every field for all $n_1, n_2 \geq 2$.