Dementia-causing substance turns into a therapeutic 'switch' with new Alzheimer's drug strategy

A substance that worsens dementia has become a "switch" that initiates treatment.

KAIST researchers have developed a new therapeutic approach that uses hydrogen peroxide (H₂O₂), a reactive oxygen species that damages cells and increases in the brains of patients with Alzheimer's disease, to activate a drug selectively in diseased brain tissue.

The team also confirmed improvements in cognitive function through animal experiments, presenting a new possibility for next-generation dementia treatment. ...