Orthogonal Integrated Conditional Moment Tests for Treatment Effect Heterogeneity

We propose a nonparametric integrated conditional moment (ICM) test for treatment effect heterogeneity across subpopulations defined by a given covariate subvector.

Under unconfoundedness, the null is recast as a conditional moment restriction based on a Neyman-orthogonal score, which reduces the first-order sensitivity of the empirical process to nuisance parameter estimation.

The test statistics are constructed as continuous functionals of a marked empirical process.

We establish a uniform feasible-to-oracle approximation and derive the asymptotic properties of these test statistics under the null and fixed alternatives.

We further show that the test has nontrivial power against local alternatives converging to the null at the $n^{-1/2}$ rate, and develop an easy-to-implement multiplier bootstrap for feasible inference.

We also develop extensions to tests of parametric CATE specifications and to settings with endogenous treatment and a binary instrument.

Finally, we apply the proposed testing approach to study whether the effect of maternal smoking during pregnancy on infant birth weight varies with maternal age.