Scientists finally solved how a common gut bacterium triggers colon cancer

Researchers solved a long-standing mystery behind how a bacterial toxin associated with colorectal cancer damages the colon.

The toxin first binds to a receptor called claudin-4, giving it access to attack the cells' protective barrier.

After identifying this weak point, the team designed a decoy protein that successfully blocked the toxin in mice.

The discovery could pave the way for new therapies to prevent inflammation and colon tumors. ...