Pangenome graph unlocks 20 near-complete variant groups in Japanese genomes

The race to complete the human pangenome—which comprises all genetic information across the human species—has been underway since 2022, when the first complete reference human genome sequence was released by the international Telomere-to-Telomere Consortium.

Now, a team led by scientists at the Research Organization of Information and Systems has made a significant contribution to a more complete understanding of human genetics with 20 near-complete variant groups located in disease- and immune-related regions from 10 Japanese men. ...