Licensed Zaire Ebola vaccine may offer partial protection against Bundibugyo outbreak

Ebolaviruses are among the most dangerous known human pathogens.

Three ebolavirus species have repeatedly caused major disease outbreaks on the African continent.

Most outbreaks have been caused by Zaire ebolavirus.

Vaccines and therapeutics are available for this virus species.

In contrast, no therapeutics or vaccines are currently available against Bundibugyo ebolavirus, which is responsible for the ongoing outbreak in the Democratic Republic of the Congo and Uganda.

This significantly complicates efforts to control the outbreak, which is already the largest documented Bundibugyo ebolavirus outbreak to date. ...